Melanocyte-Stimulating Hormone (MSH)
A critical factor in intestinal permeability/leaky gut syndrome
Compiled by Melissa Kaplan
Melanocyte-stimulating hormones (MSH) are peptide hormones secreted by the intermediate lobe of the pituitary. They stimulate melanin release and dispersal. MSH are also found in the brain where they may play a signaling role. Melanocytes are special cells in the skin and eye that synthesize melanin pigments. Clusters of melanocytes may occur on the skin, called moles.
Because MSH are so closely aligned with our skin, it's no surprise that it is surprising to find that one of the MSH, alpha-MSH, apparently plays a critical role in the ability of our gut to function properly.
The following articles go into the link between MSH, neurotoxins, and MSH's effect on gut integrity.
modulates experimental inflammatory bowel disease
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